10 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/21/1957 | A | Evansville | W | 33 | 7 | 1-0 | 3,350 | Evansville | Ind. | Reitz Bowl | |||||
| 09/27/1957 | A | Eastern Kentucky | W | 40 | 14 | 2-0 | Richmond | Ky. | |||||||
| 10/05/1957 | H | Toledo | W | 48 | 20 | 3-0 | 6,500 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/12/1957 | A | Murray State | W | 35 | 0 | 4-0 | 4,000 | Murray | Ky. | Cutchin Stadium | |||||
| 10/19/1957 | H | Dayton | W | 33 | 19 | 5-0 | 12,250 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/26/1957 | H | Central Michigan | W | 40 | 0 | 6-0 | 5,500 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 11/09/1957 | A | Kent State | L | 7 | 13 | 6-1 | 500 | Kent | Ohio | Memorial Stadium | |||||
| 11/16/1957 | H | Ohio | W | 40 | 7 | 7-1 | 5,500 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 11/22/1957 | H | Morehead State | W | 40 | 6 | 8-1 | 3,000 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 01/01/1958 | N | Drake | W | 34 | 20 | 9-1 | 9,000 | El Paso | Texas | Kidd Field | Sun Bowl |