10 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/19/1964 | H | Western Michigan | L | 7 | 10 | 0-1 | 9,084 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 09/26/1964 | A | Southern Illinois | L | 6 | 7 | 0-2 | 12,500 | Carbondale | Ill. | ||||||
| 10/03/1964 | H | North Texas | L | 0 | 22 | 0-3 | 0-2 | 10,928 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/10/1964 | A | Dayton | W | 21 | 7 | 1-3 | 0-2 | 11,750 | Dayton | Ohio | Baujan Field | ||||
| 10/17/1964 | H | Tulsa | L | 0 | 58 | 1-4 | 0-3 | 11,536 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/24/1964 | A | Marshall | L | 6 | 28 | 1-5 | 0-3 | 9,500 | Huntington | W.Va. | Fairfield Stadium | ||||
| 10/31/1964 | A | Wichita State | L | 15 | 23 | 1-6 | 0-4 | 8,310 | Wichita | Kan. | |||||
| 11/07/1964 | H | Kent State | L | 7 | 14 | 1-7 | 0-4 | 5,675 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 11/14/1964 | A | Memphis | L | 0 | 34 | 1-8 | 0-4 | 11,698 | Memphis | Tenn. | Crump Stadium | ||||
| 11/21/1964 | H | Drake | L | 8 | 14 | 1-9 | 0-4 | 1,997 | Louisville | Ky. | Fairgrounds Stadium |