9 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/17/1960 | A | Tennessee Tech | L | 7 | 21 | 0-1 | 4,500 | Cookeville | Tenn. | Overall Field | |||||
| 09/23/1960 | H | Eastern Kentucky | W | 28 | 7 | 1-1 | 3,100 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 09/30/1960 | H | Bradley | W | 40 | 6 | 2-1 | 4,897 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/07/1960 | H | Murray State | W | 12 | 6 | 3-1 | 7,935 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/15/1960 | A | Dayton | W | 36 | 0 | 4-1 | 13,000 | Dayton | Ohio | University of Dayton Stadium | |||||
| 10/21/1960 | H | Western Kentucky | W | 44 | 0 | 5-1 | 5,000 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 10/29/1960 | A | Marshall | W | 7 | 0 | 6-1 | 5,000 | Huntington | W.Va. | Fairfield Stadium | |||||
| 11/05/1960 | H | Xavier | L | 0 | 29 | 6-2 | 6,500 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 11/11/1960 | H | Kent State | W | 22 | 8 | 7-2 | Louisville | Ky. | Fairgrounds Stadium |