10 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/16/1972 | H | Kent State | W | 34 | 0 | 1-0 | 20,122 | Louisville | Ky. | Fairgrounds Stadium | |||||
| 09/30/1972 | A | Dayton | W | 28 | 11 | 2-0 | 11,214 | Dayton | Ohio | Baujan Field | |||||
| 10/07/1972 | A | Tampa | W | 17 | 14 | 3-0 | 19,437 | Tampa | Fla. | Tampa Stadium | |||||
| 10/14/1972 | H | North Texas | W | 56 | 6 | 4-0 | 1-0 | 18,041 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/21/1972 | A | Wichita State | W | 46 | 3 | 5-0 | 2-0 | 22,521 | Wichita | Kan. | Cessna Stadium | ||||
| 10/28/1972 | A | Cincinnati | W | 38 | 13 | 6-0 | 2-0 | 11,261 | Cincinnati | Ohio | Nippert Stadium | ||||
| 11/04/1972 | H | Tulsa | 17 | L | 26 | 28 | 6-1 | 2-1 | 24,000 | Louisville | Ky. | Fairgrounds Stadium | |||
| 11/11/1972 | A | Southern Illinois | W | 20 | 16 | 7-1 | 2-1 | 5,800 | Carbondale | Ill. | McAndrew Stadium | ||||
| 11/18/1972 | H | Memphis | W | 17 | 0 | 8-1 | 3-1 | 18,218 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 11/25/1972 | H | Drake | W | 27 | 0 | 9-1 | 4-1 | 14,012 | Louisville | Ky. | Fairgrounds Stadium |