10 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/24/1966 | A | Southern Illinois | W | 16 | 7 | 1-0 | 10,000 | Carbondale | Ill. | ||||||
| 10/01/1966 | H | North Texas | L | 19 | 20 | 1-1 | 0-1 | 10,000 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/08/1966 | A | Dayton | L | 17 | 20 | 1-2 | 0-1 | Dayton | Ohio | Baujan Field | |||||
| 10/15/1966 | H | Drake | W | 66 | 26 | 2-2 | 0-1 | 8,000 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/22/1966 | A | Marshall | W | 35 | 15 | 3-2 | 0-1 | 9,500 | Huntington | W.Va. | Fairfield Stadium | ||||
| 10/29/1966 | A | Wichita State | L | 2 | 9 | 3-3 | 0-2 | 7,133 | Wichita | Kan. | |||||
| 11/05/1966 | H | Kent State | W | 23 | 20 | 4-3 | 0-2 | 5,000 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 11/12/1966 | A | Cincinnati | L | 3 | 17 | 4-4 | 0-3 | 10,000 | Cincinnati | Ohio | Nippert Stadium | ||||
| 11/19/1966 | H | Tulsa | W | 29 | 18 | 5-4 | 1-3 | 3,500 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 11/26/1966 | H | East Carolina | W | 21 | 7 | 6-4 | 1-3 | 4,500 | Louisville | Ky. | Fairgrounds Stadium |