7 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/06/2026 | N | 9 | Mississippi | 24 | L | 38 | 41 | 0-1 | 57,390 | Nashville | Tenn. | Nissan Stadium | Liberty Mutual Music City Kickoff | ||
| 09/11/2026 | H | Villanova | 24 | W | 59 | 13 | 1-1 | 46,385 | Louisville | Ky. | L&N Federal Credit Union Stadium | ||||
| 09/19/2026 | H | 16 | Southern Methodist | 23 | W | 41 | 31 | 2-1 | 1-0 | 50,199 | Louisville | Ky. | L&N Federal Credit Union Stadium | ||
| 09/26/2026 | H | Wake Forest | 16 | L | 27 | 30 | 2-2 | 1-1 | 46,042 | Louisville | Ky. | L&N Federal Credit Union Stadium | |||
| 10/03/2026 | A | North Carolina State | L | 28 | 31 | 2-3 | 1-2 | 56,919 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 10/09/2026 | H | Florida State | W | 44 | 20 | 3-3 | 2-2 | 48,992 | Louisville | Ky. | L&N Federal Credit Union Stadium | ||||
| 10/17/2026 | A | Syracuse | W | 34 | 26 | 4-3 | 3-2 | 39,293 | Syracuse | N.Y. | JMA Wireless Dome |